Addressing the faithful in his Christmas Eve midnight mass in Bethlehem on Tuesday, Latin Patriarch Fuad Twal urged "men of good will" to seek peace amid "the sufferings in the Middle East."
Thousands of Palestinians and tourists were flocking to the West Bank city of Bethlehem on Monday to mark Christmas at the site where many believe Jesus Christ was born.
Israeli Prime Minister Benjamin Netanyahu was due in Berlin on Wednesday for talks likely to focus on the growing crisis over settlement plans that could torpedo the viability of a Palestinian state.
The UN General Assembly on Thursday overwhelmingly voted to make Palestine a non-member state, inflicting a major diplomatic defeat on the United States and Israel.
The US administration must radically rethink ways to achieve a sustainable Israeli-Arab peace deal or risk seeing the goal of a two-state solution slip away.
Syrian rebels on Sunday seized the training camp of a pro-regime Palestinian faction in Damascus province and took control of an arms depot after fierce clashes.
One of the Middle East's greatest political mysteries will come a step closer to being solved on Tuesday when scientists exhume iconic Palestinian leader Yasser Arafat's remains to see if he was poisoned.
Israel restricted Palestinian access to Jerusalem's Al-Aqsa mosque compound and kept a tight grip on security as a first fatality tested a hard-won truce ending fighting in and around Gaza.
Israeli politicians on Thursday returned to the campaign trail as the streets of Gaza came back to life after a truce ended eight days of bloodshed, with both sides claiming victory while remaining wary.
Oil prices fell in Asia Friday in thin trade following the US Thanksgiving holiday, with a truce in Gaza and gloomy eurozone manufacturing data weighing on buying sentiment.
A ceasefire took hold Thursday in and around Gaza after a week of cross-border violence between Israel and Palestinian militants that killed at least 160 people.
Israel's President Shimon Peres accused Iran Monday of encouraging the Palestinians to continue rocket attacks on Israel rather than negotiating a ceasefire, saying "they are out of their mind."
Israel on Tuesday halted a threatened Gaza ground offensive to give Egyptian-led truce talks a chance as top diplomats flew in to boost efforts to end nearly a week of cross-border violence.
Israeli leaders Tuesday discussed an Egyptian plan for a truce with Gaza's ruling Hamas, reports said, before a mission by the UN chief to Jerusalem and as the toll from Israeli raids on Gaza rose over 100.
A ceasefire between Israel and armed groups in Gaza depends on each side's ability to claim victory and the credibility of the mediation, undermined by Israel launching strikes with a truce already in effect.
French Foreign Minister Laurent Fabius said on Sunday a ceasefire between Israel and Gaza militants was an urgent necessity and France was willing to help broker a truce.