EU foreign policy chief Federica Mogherini urged Israel Premier Benjamin Netanyahu and Palestinian president Mahmud Abbas to meet Quartet representatives "within days" in the hope of kick-starting stalled peace talks.
Prime Minister Nawaz Sharif urged the United States to take Pakistan's side in its long-standing dispute with rival nuclear power India or run the risk of escalating conflict.
US Secretary of State John Kerry said he will engage Israeli and Palestinian leaders on the "basics" of administering Jerusalem's holy sites to try to calm tempers in the city.
US State Secretary John Kerry called for an end to the wave of deadly Israeli-Palestinian violence but said "Israel has every right in the world to protect itself".
US Secretary of State John Kerry has called the Israeli and Palestinian leaders to express concern at recent violence and ask them to work to restore calm.
NATO secretary general Jens Stoltenberg said he welcomed President Barack Obama's decision to keep US troops in Afghanistan longer than planned as part of a "crucial" effort to support Kabul.
President Vladimir Putin said that Russia would not deploy ground troops to Syria, where it has been conducting air strikes against what it says are Islamic State target.
Pope Francis deplored the "escalation of violence affecting innocent civilians" in the Middle East, from Syria to Iraq, Jerusalem and the West Bank, and urged the international community to act.
President Petro Poroshenko said a "real truce" had begun in Ukraine but that a long-lasting peace with pro-Russian insurgents would still take some time.
British Prime Minister David Cameron urged Russian President Vladimir Putin to "change direction" in Syria and recognise that its President Bashar al-Assad must be replaced.
Prime Minister Benjamin Netanyahu said Israel was "waging a fight to the death against Palestinian terror", and ordered tough new measures after the killing of two Israelis in Jerusalem.
The Syrian crisis can only be solved through peaceful ways, Kazakhstan’s Foreign Affairs Minister Yerlan Idrissov said at the General Policy Debates at the UN headquarters in New York.
Russia rejected accusations that Moscow had bombed moderate rebel factions fighting President Bashar al-Assad instead of Islamic State fighters and had hit civilians.
Turkish President Recep Tayyip Erdogan, a fierce critic of Bashar al-Assad, suggested for the first time that the Syrian president could have a role to play in a future political transition.
