Former CIA chief General David Petraeus said sorry Tuesday for the "mistake" which triggered his resignation last year, in his first public speech since quitting due to an extra-marital affair.
US President Barack Obama Tuesday named Julia Pierson as the first female chief of the Secret Service, the elite protection branch sullied by a prostitution scandal in Colombia last year.
The immigrant owner of a US convenience store claimed a $338.3 million lottery jackpot Tuesday and said that, despite being catapulted into the ranks of the super rich, his heart won't change.
The US Supreme Court trod cautiously Tuesday as it considered gay marriage, with justices appearing hesitant to deliver a sweeping historic verdict on the emotionally charged issue.
A bidding war broke out Monday for US computer maker Dell as two new acquisition offers emerged in competition with the private buyout led by founder Michael Dell.
US President Barack Obama said Monday the time has come to reform America's "broken" immigration policy, renewing his appeal to lawmakers to clinch a deal that he said is now within reach.
Supporters and opponents of same-sex marriage are prepared to turn out in force in Washington on Tuesday, when the US Supreme Court hears oral arguments in a landmark case.
US Secretary of State John Kerry vowed in Kabul to stick by Afghanistan as President Hamid Karzai, after a series of fiery outbursts, hailed a "good day" for ties with the handover of a military jail.
North Korea's military put its "strategic" rocket units on a war footing Tuesday, with a fresh threat to strike targets on the US mainland, Hawaii and Guam, as well as South Korea.
Emily Whitehead is kind of a big deal. At age seven, she is the only child to have beaten back leukemia with the help of a new treatment that turned her own immune cells into targeted cancer killers.
A new South Korea-US pact providing for a joint military response even to low-level provocation by North Korea offers an added deterrent at a time of elevated tension.
Afghanistan is set Monday to take full control of Bagram military jail from the United States, drawing a line under one running sore in their relationship as US-led forces wind down more than a decade of war.
Several hundred people marched in New York on Sunday to support the legalization of gay marriage, two days before the US Supreme Court is due to examine the issue.
Scientists said Sunday they had found mutations in 26 genes that may cause oesophageal cancer, a breakthrough they hope will lead to new drugs for the deadly and increasingly frequent disease.
NASA's Curiosity rover, which has been exploring Mars since it landed to much fanfare last August, is back on active status Tuesday, after a memory glitch set the robot back.
Could New York hold the record for most pot possession arrests? A new report out Tuesday said police there spent about a million hours taking offenders into custody between 2002 and 2012.